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Volume 8, Issue 2-3, Pages 91-96

Liposarcoma of the Thyroid

1St. Thomas’ and Guys’ Cancer Centre, Lambeth Palace Road, London, UK
2Thyroid and Sarcoma Units, Royal Marsden Hospital, London, UK
3Meyerstein Institute Of Oncology, The Middlesex Hospital, Mortimer Street, London W1T 3AA, UK

Copyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Liposarcoma of the thyroid gland is rare with only 3 cases reported in the English literature. We present a further two patients whom we have recently treated: a 49 year old lady with a myxoid liposarcoma and a 71 year old man with a pleomorphic liposarcoma. Both underwent macroscopic excision of tumour but had positive margins, so were then treated with external beam radiotherapy. The former patient died from metastases 10 months after presentation, the latter remains alive but has developed metastatic disease on follow up at 24 months.

We recommend the use of high dose radiotherapy following radical surgery as margins of excision are usually narrow in this most difficult region. The role of chemotherapy is yet to be established.