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Sarcoma
Volume 2006 (2006), Article ID 52140, 3 pages
http://dx.doi.org/10.1155/SRCM/2006/52140
Case Report

Primary Intracranial Leiomyosarcoma: Report of a Case and Review of the Literature

1Department of Medicine, Feist Weiller Cancer Center, Louisiana State University Health Science Center - Shreveport, 1501 Kings Highway, Shreveport 71130, LA, USA
2Department of Neurosurgery, Feist Weiller Cancer Center, Louisiana State University Health Science Center - Shreveport, 1501 Kings Highway, Shreveport 71130, LA, USA
3Department of Pathology, Feist Weiller Cancer Center, Louisiana State University Health Science Center - Shreveport, 1501 Kings Highway, Shreveport 71130, LA, USA
4Department of Radiology, Feist Weiller Cancer Center, Louisiana State University Health Science Center - Shreveport, 1501 Kings Highway, Shreveport 71130, LA, USA

Received 29 June 2006; Revised 13 October 2006; Accepted 13 October 2006

Copyright © 2006 Sakeer Hussain et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A 26-year old man presented with a 3-month history of a progressively enlarging palpable parieto-occipital mass. A CT scan indicated the lesion arose from the dura with bony destruction. A stealth assisted craniotomy was performed with the provisional diagnosis of osteoblastic meningioma. Further histopathologic analysis of the intracranial mass was consistent with leiomyosarcoma. Staging evaluation, including CT and PET scans, demonstrated no other sites of disease. Despite complete surgical resection and radiotherapy to the resection site, the disease recurred locally and systematically 5 months later. Primary intracranial mesenchymal tumors are rare and few cases have been previously reported. Outcomes have been universally poor and current therapeutic approaches appear to have only limited benefit.