Research Article

Synergism of Heat Shock Protein 90 and Histone Deacetylase Inhibitors in Synovial Sarcoma

Table 1

Comparison of IC50 values at 24- and 48 hour Timepoints for MS-275 and 17-AAG as single agents and in combination using MTT assay.

Timepoint (hrs) IC50 average
MS-275 17-AAG Combination (μM)
(μM) (μM) MS-27517-AAG

244.52.10.60.25
480.560.320.30.12