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Sarcoma
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Special Issues
Sarcoma
/
2009
/
Article
/
Tab 1
/
Research Article
Synergism of Heat Shock Protein 90 and Histone Deacetylase Inhibitors in Synovial Sarcoma
Table 1
Comparison of IC
50
values at 24- and 48 hour Timepoints for MS-275 and 17-AAG as single agents and in combination using MTT assay.
Timepoint (hrs)
IC
50
average
MS-275
17-AAG
Combination (
μ
M)
(
μ
M)
(
μ
M)
MS-275
17-AAG
24
4.5
2.1
0.6
0.25
48
0.56
0.32
0.3
0.12