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Volume 2010, Article ID 317462, 14 pages

UK Guidelines for the Management of Bone Sarcomas

1Royal Orthopaedic Hospital, Birmingham B31 2AP, UK
2Nuffield Orthopaedic Centre, Oxford OX3 7LD, UK
3Freeman Hospital, Newcastle-upon-Tyne NE7 7DN, UK
4The Royal Marsden, Sutton SM2 5PT, UK
5Leeds Teaching Hospitals, LS9 7TF, UK
6Birmingham Children’s Hospital, B4 6NH, UK
7Queen Elizabeth Hospital, Birmingham B15 2TH, UK
8University College Hospital, London NW1 2BU, UK

Received 10 September 2010; Accepted 20 October 2010

Academic Editor: Ole Nielsen

Copyright © 2010 Robert Grimer et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


These guidelines have been developed in order to provide an overview and a set of broad-based key recommendations for the management of patients with bone sarcomas in the UK. They have taken into consideration the most up-to-date scientific literature along with the recent recommendations by the European Society of Medical Oncology. The principles of the NICE guidance on both “improving outcomes for patients with sarcomas” and “improving outcomes with children and young people with cancer” have been incorporated. As care evolves, it is acknowledged that these guidelines will need updating. The key recommendations are that bone pain or a palpable mass should always lead to further investigation and patients with clinicoradiological findings suggestive of a primary bone tumour should be sent to a reference centre. Patients should then have their care managed at such a specialist centre by a fully accredited multidisciplinary team.