Sarcoma / 2010 / Article / Tab 3

Guidelines

Guidelines for the Management of Soft Tissue Sarcomas

Table 3

S uggested managment of extremity STS - adapted from ESMO guidance.

Adultsoft tissue sarcoma Standard Individualized Investigational
Extremities or superficial trunk

Primary, low-grade, superficialSurgery: wide excision
Primary, low-grade, deep and 5 cmSurgery: wide excision
Primary, low-grade, deep and >5 cmSurgery: wide excision ± adjuvant radiation therapy
Primary, high-grade, superficialSurgery: wide excision
Primary, high-grade, deep, 5 cmSurgery: wide excisionSurgery: wide excision + adjuvant radiation therapy OR compartmental resection
Primary, high-grade, deep, >5 cmSurgery: wide excision + adjuvant radiation therapy (pre and/OR post)Surgery: wide excision + adjuvant radiation therapy (pre and/OR post) + Discussion of adjuvant ChemotherapyNeoadjuvant chemotherapy ± postoperative chemotherapy followed by Wide surgical excision + adjuvant postoperative (or preoperative) radiation therapy
Compartmental resectionCompartmental resection + Discussion of adjuvant Chemotherapy
Local recurrence, low-gradeSurgery: wide excision + adjuvant radiation therapy (pre and/OR post)Surgery: wide excisionIsolated limb perfusion
Local recurrence, high-gradeSurgery: wide excision + adjuvant radiation therapySurgery: wide excision + Adjuvant Radiation therapy + Discussion of Adjuvant ChemotherapyIsolated limb perfusion
Surgery: compartmental resectionSurgery: compartmental resection + Discussion of Adjuvant Chemotherapy

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.