Research Article

Clinical Features, Treatment, and Outcome in 102 Adult and Pediatric Patients with Localized High-Grade Synovial Sarcoma

Table 3

Univariate analysis of prognostic factors in adult and pediatric SS.

Variable5-year EFSnP

Size<5 cm62 ± 6.3%35.03
≥5 cm82 ± 6.7%65

DepthSuperficial81.8 ± 11.6%12.35
Deep69.1 ± 5.1%89

Microscopic margin statusPositive62.5 ± 17.1%94.62
Negative70.4 ± 5.0%8

CenterPediatric74.9 ± 13.0%15.31
Adult68.7 ± 5.1%87

Age≤3070.9 ± 6.7%51.47
>3068.6 ± 6.8%51

Bone invasionPresent45 ± 17.4% 10.02
Absent74.5 ± 5.1%80

Neurovascular invasionPresent60.0 ± 21.9%6.87
Absent71.8 ± 5.2%84

RadiationYes69.6 ± 5.4%80.67
No67.5 ±11%21

ChemotherapyYes62.6 ± 11.2%25.48
No71.5 ± 5.3%77

AdultsChemotherapy56.3 ± 14.8%12.13
No chemo70.7 ± 5.4%75

PediatricChemotherapy69.2 ± 15.6%13.41
No chemo100%2

>5 cmChemotherapy51.3 ±13.4%19.37
No chemo65.7 ±7.2%46