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Sarcoma
Volume 2011, Article ID 457532, 4 pages
http://dx.doi.org/10.1155/2011/457532
Review Article

Ewing Sarcoma: An Eponym Window to History

1Division of Hematology/Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, ML7015, OH 45229, USA
2University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA

Received 27 June 2010; Accepted 30 October 2010

Academic Editor: R. Pollock

Copyright © 2011 Timothy P. Cripe. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. R. Zantinga and M. J. Coppes, “James Ewing (1866–1943): 'The Chief',” Medical and Pediatric Oncology, vol. 21, no. 7, pp. 505–510, 1993. View at Google Scholar · View at Scopus
  2. A. G. Huvos, “James Ewing: cancer man,” Annals of Diagnostic Pathology, vol. 2, no. 2, pp. 146–148, 1998. View at Google Scholar · View at Scopus
  3. Unknown, “Medicine: Cancer Crusade,” Time Magazine, 1931, http://www.time.com/time/magazine/article/0,9171,930304,930300.html.
  4. J. Ewing, “Diffuse endothelioma of bone,” Proceedings of the New York Pathological Society, vol. 21, p. 17, 1921. View at Google Scholar
  5. W. Coley, “The treatment of malignant tumors by repeated inoculations of erysipelas: with a report of ten original cases,” American Journal of the Medical Sciences, vol. 105, pp. 487–511, 1893. View at Google Scholar
  6. G. Rosen, N. Wollner, and C. Tan, “Disease free survival in children with Ewing's sarcoma treated with radiation therapy and adjuvant four drug sequential chemotherapy,” Cancer, vol. 33, no. 2, pp. 384–393, 1974. View at Google Scholar
  7. M. A. Smith, N. L. Seibel, S. F. Altekruse et al., “Outcomes for children and adolescents with cancer: challenges for the twenty-first century,” Journal of Clinical Oncology, vol. 28, no. 15, pp. 2625–2634, 2010. View at Publisher · View at Google Scholar
  8. D. H. James Jr. and P. George, “Vincristine in children with malignant solid tumors,” The Journal of Pediatrics, vol. 64, no. 4, pp. 534–541, 1964. View at Google Scholar · View at Scopus
  9. C. Tan, H. Tasaka, K. P. Yu, M. L. Murphy, and D. A. Karnofsky, “Daunomycin, an antitumor antibiotic, in the treatment of neoplastic disease. Clinical evaluation with special reference to childhood leukemia,” Cancer, vol. 20, no. 3, pp. 333–353, 1967. View at Google Scholar · View at Scopus
  10. M. L. Samuels and C. D. Howe, “Cyclophosphamide in the management of Ewing's sarcoma,” Cancer, vol. 20, no. 6, pp. 961–966, 1967. View at Google Scholar · View at Scopus
  11. R. E. Cupps, D. L. Ahmann, and E. H. Soule, “Treatment of pulmonary metastatic disease with radiation therapy and adjuvant actinomycin D. Preliminary observations,” Cancer, vol. 24, no. 4, pp. 719–723, 1969. View at Google Scholar · View at Scopus
  12. R. L. Chard Jr., W. Krivit, W. A. Bleyer, and D. Hammond, “Phase II study of VP-16-213 in childhood malignant disease: a children's cancer study group report,” Cancer Treatment Reports, vol. 63, no. 11-12, pp. 1755–1759, 1979. View at Google Scholar · View at Scopus
  13. C. R. Pinkerton, H. Rogers, and C. James, “A phase II study of ifosfamide in children with recurrent solid tumours,” Cancer Chemotherapy and Pharmacology, vol. 15, no. 3, pp. 258–262, 1985. View at Google Scholar
  14. W. H. Meyer, L. Kun, N. Marina et al., “Ifosfamide plus etoposide in newly diagnosed Ewing's sarcoma of bone,” Journal of Clinical Oncology, vol. 10, no. 11, pp. 1737–1742, 1992. View at Google Scholar · View at Scopus
  15. C. Turc-Carel, I. Philip, and M. P. Berger, “Chromosomal translocation t(11;22) (q24;q12) in cell lines derived from Ewing sarcoma,” Comptes Rendus des Seances de l'Academie des Sciences III, vol. 296, no. 23, pp. 1101–1103, 1983. View at Google Scholar · View at Scopus
  16. C. de Taisne, A. Gegonne, and D. Stehelin, “Chromosomal localization of the human proto-oncogene c-ets,” Nature, vol. 310, no. 5978, pp. 581–583, 1984. View at Google Scholar · View at Scopus
  17. J. Zucman, O. Delattre, C. Desmaze et al., “Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints,” Genes Chromosomes and Cancer, vol. 5, no. 4, pp. 271–277, 1992. View at Publisher · View at Google Scholar · View at Scopus
  18. E. F. Marley, H. Liapis, P. A. Humphrey et al., “Primitive neuroectodermal tumor of the kidney—another enigma: a pathologic, immunohistochemical, and molecular diagnostic study,” American Journal of Surgical Pathology, vol. 21, no. 3, pp. 354–359, 1997. View at Publisher · View at Google Scholar · View at Scopus
  19. G. L. Floersheim, A. Bieri, and N. Chiodetti, “Xenografts in pharmacologically immunosuppressed mice as a model to test the chemotherapeutic sensitivity of human tumors,” International Journal of Cancer, vol. 37, no. 1, pp. 109–114, 1986. View at Google Scholar · View at Scopus
  20. C. Frouge, D. Vanel, C. Coffre, D. Couanet, G. Contesso, and D. Sarrazin, “The role of magnetic resonance imaging in the evaluation of Ewing sarcoma. A report of 27 cases,” Skeletal Radiology, vol. 17, no. 6, pp. 387–392, 1988. View at Google Scholar · View at Scopus
  21. B. L. Shulkin, D. S. Mitchell, D. R. Ungar et al., “Neoplasms in a pediatric population: 2-[F-18]-fluoro-2-deoxy-D-glucose PET studies,” Radiology, vol. 194, no. 2, pp. 495–500, 1995. View at Google Scholar · View at Scopus
  22. H. Hamada and A. Uchida, “Limb salvage surgery for pelvic malignancies followed by reconstruction with hip endoprosthesis,” Japanese Journal of Cancer and Chemotherapy, vol. 15, no. 4, pp. 1535–1541, 1988. View at Google Scholar · View at Scopus
  23. C. Franzius, J. Sciuk, C. B. Schmidt, H. Jürgens, and O. Schober, “Evaluation of chemotherapy response in primary bone tumors with F-18 FDG positron emission tomography compared with histologically assessed tumor necrosis,” Clinical Nuclear Medicine, vol. 25, no. 11, pp. 874–881, 2000. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Burdach, C. Peters, M. Paulussen et al., “Improved relapse free survival in patients with poor prognosis Ewing's sarcoma after consolidation with hyperfractionated total body irradiation and fractionated high dose melphalan followed by high dose etoposide and hematopoietic rescue,” Bone Marrow Transplant, vol. 7, supplement 2, p. 95, 1991. View at Google Scholar
  25. K. M. Snyder and C. L. Mackall, “Therapy for metastatic ESFT: is it time to ask new questions?” Pediatric Blood and Cancer, vol. 49, no. 2, pp. 115–116, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. H. E. Grier, M. D. Krailo, N. J. Tarbell et al., “Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone,” New England Journal of Medicine, vol. 348, no. 8, pp. 694–701, 2003. View at Publisher · View at Google Scholar · View at Scopus
  27. R. B. Womer, R. T. Daller, J. G. Fenton, and J. S. Miser, “Granulocyte colony stimulating factor permits dose intensification by interval compression in the treatment of Ewing's sarcomas and soft tissue sarcomas in children,” European Journal of Cancer, vol. 36, no. 1, pp. 87–94, 2000. View at Google Scholar · View at Scopus
  28. R. B. Womer, D. C. West, M. D. Krailo, P. S. Dickman, and B. Pawel, “Randomized comparison of every-two-week v. every-three-week chemotherapy in Ewing sarcoma family tumors (ESFT),” Journal of Clinical Oncology, vol. 26, abstract #10504, 2008. View at Google Scholar
  29. H. V. Erkizan, Y. Kong, M. Merchant et al., “A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma,” Nature Medicine, vol. 15, no. 7, pp. 750–756, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. N. J. Balamuth and R. B. Womer, “Ewing's sarcoma,” The Lancet Oncology, vol. 11, no. 2, pp. 184–192, 2010. View at Publisher · View at Google Scholar · View at Scopus