Physeal Bystander Effects in Rhabdomyosarcoma Radiotherapy: Experiments in a New Xenograft Model

Table 2

Terminal femur, tibial, and total limb length. Data shown are mean ±1SD; ^‡differences between control and irradiated, tumor-bearing limbs were accepted as significant when 𝑃≤.05 by Student’s paired 𝑡-test.

	Femur length (mm)		Tibia length (mm)		Limb length (mm)
	Control	Irradiated	Control	Irradiated	Control	Irradiated
0 Gy
Mean ± SD	13.5 ± 0.6	13.2 ± 0.5	15.1 ± 0.6	15.1 ± 0.8	28.6 ± 0.8	28.3 ± 0.9
P^‡	𝑃=.0892		𝑃=.6467		𝑃=.3769
2 Gy
Mean ± SD	13.4 ± 0.4	12.8 ± 0.6	15.6 ± 0.4	14.9 ± 0.4	29.1 ± 0.7	27.9 ± 0.6
P^‡	𝑃=.0141		𝑃=.0156		𝑃=.0072
10 Gy
Mean ± SD	14.3 ± 0.4	13.8 ± 0.6	16.1 ± 0.3	15.6 ± 0.3	30.4 ± 0.6	29.4 ± 0.8
P^‡	𝑃=.0013		𝑃=.0123		𝑃=.0003