Review Article
Pathobiologic Markers of the Ewing Sarcoma Family of Tumors: State of the Art and Prediction of Behaviour
Table 3
Translocations reported in ESFT [
22,
67,
68].
| Translocation | Fusion gene | Per cent positive |
| t(11;22)(q24;q12) | EWS-FLI1 | 85 | t(21;22)(q22;q12) | EWS-ERG | 5–10 | t(19;der)inv(21;22) | EWS-ERG | 1 | t(7:22)(p22;q12) | EWS-ETV1 | 1 | t(17;22)(q12;q12) | EWS-ETV4 | 1 | t(2;22)(q33;q12) | EWS-FEV | 1 | t(6;22)(p21;q12) | EWS-POU5F1 | 1 | t(1;22)(q36.1;q12) | EWS-PATZI | 1 | t(2;22)(q31;q12) | EWS-SP3 | 1 | t(20;22)(q13;q12) | EWS-NFATc2 | 1 | t(16;21)(p11;q22) | FUS-ERG | 1 | t(2;16)(q35;p11) | FUS-FEV | 1 | t(4;19)(q35;q13) | CIC-DUX4 | 1 |
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