Review Article

The Bone Niche of Chondrosarcoma: A Sanctuary for Drug Resistance, Tumour Growth and also a Source of New Therapeutic Targets

Figure 2

Chondrosarcoma growth is strongly linked to the bone tissue. Relationship between bone tissue and chondrosarcoma cells (a–c). Infiltration of chondrosarcoma cells into the bone tissue (permeation) (a–c). Chondrosarcoma development is associated with bone resorption foci (b). HES staining, original magnification (×20, a and b; ×40: c). Arrow: bone resorption area, arrow head: necrosis of chondrosarcoma tissue, and *: viable tumour component.
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