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Sarcoma
Volume 2012, Article ID 350806, 6 pages
http://dx.doi.org/10.1155/2012/350806
Research Article

Incidence and Survival of Pediatric Soft Tissue Sarcomas in Moscow Region, Russian Federation, 2000–2009

1Department of Oncology and Hematology, Russian State Medical University, 1 Ostrovityanova Street, Moscow 117997, Russia
2Department of Clinical Oncology, Federal Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Street, Moscow 117198, Russia

Received 30 May 2011; Revised 9 January 2012; Accepted 15 January 2012

Academic Editor: Ajay Puri

Copyright © 2012 D. Y. Kachanov et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of the study was to assess the incidence and survival rates of soft tissue sarcomas (STSs) in children 0–14 years of age in Moscow Region, Russian Federation. The database of childhood population-based cancer registry of Moscow Region was used as a data source. Tumors were stratified according to International Classification of Childhood Cancer, 3d ed. Sixty-eight cases of STS were registered from 2000 to 2009. Crude incidence rate was 0,78, and age-standardized incidence rate using World Standard Population was 0,81 per 100.000 children/year. The highest age-specific incidence was observed in infants: 1,76 per 100.000 children/year. Rhabdomyosarcoma (RMS) was the most common histological type comprising 54,4% of all STS. 5-year observed survival (OS) of all patients with STS was 64,1 (95% CI 55,0–73,2). There was no statistically significant difference in OS between RMS—59,2 (95% CI 47,0–71,4) and nonrhabdomyosarcoma STS—69,3 (95% CI 55,8–82,8) ( 𝑃 = 0 . 6 3 ). Incidence and survival rates of STS observed in the study were comparable to the other Eastern European countries.