DNA Methylation and Gene Expression Profiling of Ewing Sarcoma Primary Tumors Reveal Genes That Are Potential Targets of Epigenetic Inactivation
Figure 2
Heat map depicting DNA hypermethylation in EWS primary tumors. 37 CpGs in 36 genes were found to be hypermethylated in >30% of EWS primary tumors () and >75% of hMSCs (). Also shown are methylation analyses of EWS cell lines A673, SK-N-MC, and SK-ES-1, respectively. Red: methylated; green: unmethylated, CL: cell lines.