Figure 2: Heat map depicting DNA hypermethylation in EWS primary tumors. 37 CpGs in 36 genes were found to be hypermethylated in >30% of EWS primary tumors ( ) and >75% of hMSCs ( ). Also shown are methylation analyses of EWS cell lines A673, SK-N-MC, and SK-ES-1, respectively. Red: methylated; green: unmethylated, CL: cell lines.