Prognostic Value of Microvessel Density in Tumor and Peritumoral Area as Evaluated by CD31 Protein Expression and Argyrophilic Nucleolar Organizer Region Count in Endothelial Cells in Uterine Leiomyosarcoma

Table 3

Significance of prognostic criteria as evaluated by Cox regression multivariate analysis.

Clinical and pathological feature	𝜒^2	𝑃
Stage (according to FIGO)	9	0.002
pTNM category	10.9	0.0009
Age	6.5	0.01
Type of surgery	0.2	0.8
Tumor size	0.17	0.7
Chemoradiotherapy	2.3	0.1
Recurrence/metastases	9.6	0.02
Grade of malignancy	14.2	0.0002
AgNOR in peritumoral area	0.01	0.9
AgNOR in tumor	1.9	0.1
MVD (CD31) in peritumoral area	27.5	0.0003
MVD (CD31) in tumor	0.1	0.8