Clinical Study

Should Aggressive Surgical Local Control Be Attempted in All Patients with Metastatic or Pelvic Ewing's Sarcoma?

Table 1

Patient characteristics.

Variable (#)Number/percentage

Age (46)
 <149 (20%)
 ≥1437 (80%)
Sex (46)
 Male28 (61%)
 Female18 (39%)
Location (46)
 Appendicular27 (59%)
 Axial19 (41%)
Pelvic (46)
 No35 (76%)
 Yes11 (24%)
Bone or soft tissue (46)
 Bone39 (85%)
 Soft tissue7 (15%)
Metastatic disease (42)
 No29 (69%)
 Yes13 (31%)
Multicentric disease (42)
 No35 (83%)
 Yes7 (17%)
Neoadjuvant chemotherapy (43)
 No6 (14%)
 Yes37 (86%)
Local radiationδ (43)
 No33 (77%)
 Yes10 (23%)
Margins (35)
 Negative26 (74%)
 Positive 9 (26%)
Local recurrence (46)
 No31 (67%)
 Yes15 (33%)
Late metastatic disease (44)
 No24 (55%)
 Yes20 (45%)
Status at last followup (46)
 AWOD23 (50%)
 AWED 6 (13%)
 DOD16 (35%)
 DWOD1 (2%)

AWOD: alive without disease.
AWED: alive with evidence of disease.
DOD: died of disease.
DWOD: died without evidence of disease.
: number of patients with sufficient data for each data point.
δ: local radiation either as primary local treatment of neoadjuvant.