Clinical Study

Outcome of Rhabdomyosarcoma in First Year of Life: Children’s Cancer Hospital 57357 Egypt

Table 1

Low risk protocol roadmap.

Weeks 1 2 3 4 5 6 78910111213
VACV VVAC V VVACVVAC ** ** VA

Weeks 141516 171819 20212223242526
VVVA VVVA VVA ** ** VAV

Weeks 272829 303132 33343536373839
VVAV VVAV VA ** ** VAVV

Weeks 404142 434445 4647
VAVV VAVV VA **

Vincristine (V): 1.5 mg/m2 (max. 2 mg) IV push.
Actinomycin (A): 0.045 mg/kg (max. 2.5 mg) IV push.
Cyclophosphamide (C): 1.2 gm/m2 IV infusion over 60 min with hydration and MESNA.
**No chemotherapy and the time of reevaluation (at weeks 12, 24, 36, and 47 end of therapy).