Rapamycin Inhibits ALDH Activity, Resistance to Oxidative Stress, and Metastatic Potential in Murine Osteosarcoma Cells
Figure 3
Rapamycin treatment reduces K7M2 cell proliferation. (a) K7M2 cells were cultured with media containing 10 μM rapamycin or DMSO only (control) for four days. Representative images of cell density at the beginning and end of treatment are shown. (b) A quantitative analysis of (a) to determine the population doubling time (PDT) of K7M2 cells in rapamycin-treated and control groups (DMSO only). (c) A quantitative analysis determining the population doubling time (PDT) of K12 cells in rapamycin-treated and control groups (DMSO only). Asterisks (*) indicate statistically significant differences ().
