Clinical Activity and Tolerability of a 14-Day Infusional Ifosfamide Schedule in Soft-Tissue Sarcoma

Table 2

Toxicity—number of patients.

Toxicity	Grade 1-2	Grade 3-4	Total
Fatigue	28 (80%)	2 (5.7%)	30 (85.7%)
Nausea	24 (68.6%)	5 (14.3%)	29 (83%)
Vomiting	16 (45.7%)	3 (8.6%)	19 (54.3%)
Myelosuppression	14 (40%)	2 (5.7%)	16 (45.7%)
Encephalopathy	6 (17.1%)	6 (17.1%)	12 (34.2%)
Constipation	10 (28.6%)	0	10 (28.6%)
Diarrhoea	4 (11.4%)	2 (5.7%)	6 (17.1%)
Renal function impairment	5 (14.3%)	0	5 (14.3%)
Liver function tests alteration	1 (2.8%)	0	1 (2.8%)