Aberrant Hedgehog Signaling and Clinical Outcome in Osteosarcoma
Expression levels of IHH, PTCH1, SMO, and GLI1 in 43 osteosarcoma tumors relative to normal osteoblasts. Expression levels in tumors were normalized to the average level of 2 normal osteoblast samples and presented as fold change. Fold changes greater than the -axis are labelled next to the representing bars (NoMetDx = no metastasis at diagnosis; MetDx = metastasis at diagnosis).
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