Sarcoma / 2014 / Article / Tab 2

Research Article

Aberrant Hedgehog Signaling and Clinical Outcome in Osteosarcoma

Table 2

Results of DFS analysis by Cox Proportional Hazards model in no metastasis at diagnosis group for IHH.

Prognostic factorUnivariateMultivariate*
HR95% CI valueHR95% CI value

IHH
 High versus low2.660.848.400.09486.430.7157.970.0970
Size
 >9 cm versus ≤9 cm3.521.0611.670.039422.812.22234.020.0085
Necrosis
 >90% versus ≤90%0.710.212.350.57160.530.132.140.3733
Gender
 Male versus female1.390.444.360.57950.220.022.250.1998
 Age (years)1.020.991.050.16761.030.991.070.0965

Firth correction to handle small sample sizes.