Sarcoma Immunotherapy: Past Approaches and Future Directions

Table 3

Cancer testis antigens expressed in sarcoma.

Antigen	Sarcoma type	Total expression
NY-ESO [110, 111, 113]	Synovial; Myxoid round cell liposarcoma; Uterine leiomyosarcoma; Osteosarcoma	80%; 100%; 50% (3/6); 89% (8/9)
LAGE [109, 112]	Myxoid round cell liposarcoma; Nonmyxoid liposarcoma; Osteosarcoma	70%; 60%; 89% (8/9)
PRAME [112]	Synovial sarcoma; Nonmyxoid liposarcoma; Myxoid liposarcoma	100% (4/4); 100% (4/4); 14% (1/7)
MAGE-A3 [109]	Uterine leiomyosarcoma; Nonuterine leiomyosarcoma	67% (4/6); 14% (1/7)