Brain Metastasis in Bone and Soft Tissue Cancers: A Review of Incidence, Interventions, and Outcomes

Table 3

Comparison of published reports on patients with brain metastases from chondrosarcoma and chordoma.

Case author	Age, sex	IB yr.	BM treatment	OS Mo
Chondrosarcoma
Flannery et al., 2010 [15]	14 M, 56 M	0.5–1.3	GKSRS	18–21
Francés-Muñoz et al., 2012 [39]	53 F	10	Chemo for lung	NR
Kawaguchi et al., 2012 [43]	54 M	0.7	Chemo	52
Jallu et al., 1992 [41]	54 F	0.7	SR	NR
Konishi et al., 1994 [44]	72 F	2	SR	2
Reyaz and Ashraf, 2006 [45]	34 F	7	SR	NR
Talerman, 1967 [46]	26 F	—	—	—
Templeton et al., 1985 [47]	15 M	34	D	NR
Waga et al., 1972 [48]	32 M	12	SR	NR
Tsutsumi et al., 2010 [40]	60 M	4.4	Chemo, GKSRS	10+
Fox et al., 1968 [49]	51 F	—	D	11
Chordoma
Kamel et al., 2005 [53]	12 M	32	SR	32 (alive)
Anderson and Meyers, 1968 [54]	69 M	24	SR (gross total)	36 (alive)
Al-Adra et al., 2011 [52]	29 M	16	SR, WBRT	?
Morris and Rabinovitch, 1947 [56]	41 M	2.5	WBRT	2.5
Fichardt and De Villiers, 1974 [55]	59 M	36	SR	42
Higinbotham et al. 1967 [50]	58 F	?	None (autopsy finding)	72
Mesgarzadeh et al., 2008 [57]	27 F	18	None	24

Chemo: chemotherapy; D: death prior to treatment; F: female; GKSRS: Gamma knife stereotactic radiosurgery; IB: interval between diagnosis of brain metastasis from chondrosarcoma in years (yr); M: male; NR: not reported; OS: overall survival in months; Radio: radiotherapy; SR: surgical resection; WBRT: whole brain radiotherapy; ^adiagnosed postmortem; ^bbrain metastasis diagnosed first; +: survival reported for at least the stated amount.