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Sarcoma
Volume 2015 (2015), Article ID 186581, 12 pages
http://dx.doi.org/10.1155/2015/186581
Research Article

The Use of Radiation Therapy in Well-Differentiated Soft Tissue Sarcoma of the Extremities: An NCDB Review

1School of Medicine, Duke University, Durham, NC 27710, USA
2Department of Surgery, Division of Orthopedic Surgery, Duke University Medical Center, Durham, NC 27710, USA
3Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
4Department of Orthopedic Surgery, National Taiwan University Hospital, Taipei 10617, Taiwan
5Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA

Received 7 February 2015; Revised 10 April 2015; Accepted 21 April 2015

Academic Editor: Peter C. Ferguson

Copyright © 2015 Alexander L. Lazarides et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Jemal, R. Siegel, J. Xu, and E. Ward, “Cancer statistics, 2010,” CA Cancer Journal for Clinicians, vol. 60, no. 5, pp. 277–300, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. R. W. Miller, J. L. Young Jr., and B. Novakovic, “Childhood cancer,” Cancer, vol. 75, supplement 1, pp. 395–405, 1995. View at Publisher · View at Google Scholar · View at Scopus
  3. G. B. Mann, J. J. Lewis, and M. F. Brennan, “Adult soft tissue sarcoma,” Australian and New Zealand Journal of Surgery, vol. 69, no. 5, pp. 336–343, 1999. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Sinha and A. H. S. Peach, “Diagnosis and management of soft tissue sarcoma,” British Medical Journal, vol. 341, Article ID c7170, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Hussein and M. A. Smith, “Soft tissue sarcomas: are current referral guidelines sufficient?” Annals of the Royal College of Surgeons of England, vol. 87, no. 3, pp. 171–173, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. P. F. M. Choong, I. A. Petersen, A. G. Nascimento, and F. H. Sim, “Is radiotherapy important for low-grade soft tissue sarcoma of the extremity?” Clinical Orthopaedics and Related Research, no. 387, pp. 191–199, 2001. View at Google Scholar · View at Scopus
  7. G. K. Zagars, M. T. Ballo, P. W. T. Pisters et al., “Prognostic factors for patients with localized soft-tissue sarcoma treated with conservation surgery and radiation therapy: an analysis of 1225 patients,” Cancer, vol. 97, no. 10, pp. 2530–2543, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. J. C. Yang, A. E. Chang, A. R. Baker et al., “Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity,” Journal of Clinical Oncology, vol. 16, no. 1, pp. 197–203, 1998. View at Google Scholar · View at Scopus
  9. P. W. Pisters, L. B. Harrison, D. H. Leung, J. M. Woodruff, E. S. Casper, and M. F. Brennan, “Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma,” Journal of Clinical Oncology, vol. 14, no. 3, pp. 859–868, 1996. View at Google Scholar · View at Scopus
  10. S. M. M. Sommerville, J. T. Patton, J. C. Luscombe, D. C. Mangham, and R. J. Grimer, “Clinical outcomes of deep atypical lipomas (well-differentiated lipoma-like liposarcomas) of the extremities,” ANZ Journal of Surgery, vol. 75, no. 9, pp. 803–806, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Koshy, S. E. Rich, and M. M. Mohiuddin, “Improved survival with radiation therapy in high-grade soft tissue sarcomas of the extremities: a SEER analysis,” International Journal of Radiation Oncology Biology Physics, vol. 77, no. 1, pp. 203–209, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. National-Comprehensive-Cancer-Network, Soft Tissue Sarcoma Version 2.2014, 2014, http://www.nccn.org/professionals/physician_gls/PDF/sarcoma.pdf.
  13. P. R. Rosenbaum and D. B. Rubin, “The central role of the propensity score in observational studies for causal effects,” Biometrika, vol. 70, no. 1, pp. 41–55, 1983. View at Publisher · View at Google Scholar · View at MathSciNet · View at Scopus
  14. S. Singer, C. R. Antonescu, E. Riedel, M. F. Brennan, and R. E. Pollock, “Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma,” Annals of Surgery, vol. 238, no. 3, pp. 358–371, 2003. View at Google Scholar · View at Scopus
  15. M. F. Brennan, C. R. Antonescu, N. Moraco, and S. Singer, “Lessons learned from the study of 10,000 patients with soft tissue sarcoma,” Annals of Surgery, vol. 260, no. 3, pp. 416–422, 2014. View at Publisher · View at Google Scholar
  16. R. Kandel, N. Coakley, J. Werier, J. Engel, M. Ghert, and S. Verma, “Surgical margins and handling of soft-tissue sarcoma in extremities: a clinical practice guideline,” Current Oncology, vol. 20, no. 3, pp. e247–e254, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. K. K. Tanabe, R. E. Pollock, L. M. Ellis, A. Murphy, N. Sherman, and M. M. Romsdahl, “Influence of surgical margins on outcome in patients with preoperatively irradiated extremity soft tissue sarcomas,” Cancer, vol. 73, no. 6, pp. 1652–1659, 1994. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Alho, T. A. Alvegard, O. Berlin et al., “Surgical margin in soft tissue sarcoma. The Scandinavian Sarcoma Group experience,” Acta Orthopaedica Scandinavica, vol. 60, no. 6, pp. 687–692, 1989. View at Publisher · View at Google Scholar · View at Scopus
  19. A. Azzarelli, “Surgery in soft tissue sarcomas,” European Journal of Cancer Part A: General Topics, vol. 29, no. 4, pp. 618–623, 1993. View at Publisher · View at Google Scholar · View at Scopus
  20. S. A. Rosenberg, J. Tepper, E. Glatstein et al., “The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy,” Annals of Surgery, vol. 196, no. 3, pp. 305–315, 1982. View at Google Scholar
  21. C. S. Trovik, “Local recurrence of soft tissue sarcoma: a Scandinavian sarcoma group project,” Acta Orthopaedica Scandinavica—Supplement, vol. 72, no. 300, pp. 1–31, 2001. View at Google Scholar · View at Scopus
  22. J. C. Gutierrez, E. A. Perez, D. Franceschi, F. L. Moffat Jr., A. S. Livingstone, and L. G. Koniaris, “Outcomes for soft-tissue sarcoma in 8249 cases from a large state cancer registry,” Journal of Surgical Research, vol. 141, no. 1, pp. 105–114, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. A. le Cesne, S. Cresta, R. G. Maki et al., “A retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas,” European Journal of Cancer, vol. 48, no. 16, pp. 3036–3044, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. N. Pervaiz, N. Colterjohn, F. Farrokhyar, R. Tozer, A. Figueredo, and M. Ghert, “A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma,” Cancer, vol. 113, no. 3, pp. 573–581, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. A. T. Deyrup and S. W. Weiss, “Grading of soft tissue sarcomas: the challenge of providing precise information in an imprecise world,” Histopathology, vol. 48, no. 1, pp. 42–50, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. C. D. Fletcher, “WHO classification of tumours of soft tissue and bone,” in World Health Organization Classification of Tumours, IARC Press, Lyon, France, 4th edition, 2013. View at Google Scholar
  27. A. Mollabashy, W. W. Virkus, R. A. Zlotecki, B. H. Berrey, and M. T. Scarborough, “Radiation therapy for low-grade soft tissue sarcoma,” Clinical Orthopaedics and Related Research, no. 397, pp. 190–195, 2002. View at Google Scholar · View at Scopus
  28. H. D. Suit, H. J. Mankin, W. C. Wood et al., “Treatment of the patient with stage M0 soft tissue sarcoma,” Journal of Clinical Oncology, vol. 6, no. 5, pp. 854–862, 1988. View at Google Scholar · View at Scopus
  29. A. Gronchi, R. Miceli, M. Fiore et al., “Extremity soft tissue sarcoma: adding to the prognostic meaning of local failure,” Annals of Surgical Oncology, vol. 14, no. 5, pp. 1583–1590, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. J. J. Lewis, D. Leung, M. Heslin, J. M. Woodruff, and M. F. Brennan, “Association of local recurrence with subsequent survival in extremity soft tissue sarcoma,” Journal of Clinical Oncology, vol. 15, no. 2, pp. 646–652, 1997. View at Google Scholar · View at Scopus
  31. B. O'Sullivan, A. M. Griffin, C. I. Dickie et al., “Phase 2 study of preoperative image-guided intensity-modulated radiation therapy to reduce wound and combined modality morbidities in lower extremity soft tissue sarcoma,” Cancer, vol. 119, no. 10, pp. 1878–1884, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. F. Roeder, B. Lehner, T. Schmitt et al., “Excellent local control with IOERT and postoperative EBRT in high grade extremity sarcoma: results from a subgroup analysis of a prospective trial,” BMC Cancer, vol. 14, no. 1, article 350, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. R. J. Canter, S. Beal, D. Borys, S. R. Martinez, R. J. Bold, and A. S. Robbins, “Interaction of histologic subtype and histologic grade in predicting survival for soft-tissue sarcomas,” Journal of the American College of Surgeons, vol. 210, no. 2, pp. 191–198.e2, 2010. View at Publisher · View at Google Scholar · View at Scopus
  34. J. B. Koea, D. Leung, J. J. Lewis, and M. F. Brennan, “Histopathologic type: an independent prognostic factor in primary soft tissue sarcoma of the extremity?” Annals of Surgical Oncology, vol. 10, no. 4, pp. 432–440, 2003. View at Publisher · View at Google Scholar · View at Scopus
  35. J.-M. Coindre, P. Terrier, L. Guillou et al., “Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas: a study of 1240 patients from the French Federation of Cancer Centers sarcoma group,” Cancer, vol. 91, no. 10, pp. 1914–1926, 2001. View at Publisher · View at Google Scholar · View at Scopus
  36. D. R. Lucas, A. G. Nascimento, B. K. S. Sanjay, and M. G. Rock, “Well-differentiated liposarcoma: the Mayo Clinic experience with 58 cases,” The American Journal of Clinical Pathology, vol. 102, no. 5, pp. 677–683, 1994. View at Google Scholar · View at Scopus
  37. C. A. Smith, S. R. Martinez, W. H. Tseng et al., “Predicting survival for well-differentiated liposarcoma: the importance of tumor location,” Journal of Surgical Research, vol. 175, no. 1, pp. 12–17, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. K. M. Dalal, C. R. Antonescu, and S. Singer, “Diagnosis and management of lipomatous tumors,” Journal of Surgical Oncology, vol. 97, no. 4, pp. 298–313, 2008. View at Publisher · View at Google Scholar · View at Scopus
  39. G. K. Zagars, M. S. Goswitz, and A. Pollack, “Liposarcoma: outcome and prognostic factors following conservation surgery and radiation therapy,” International Journal of Radiation Oncology, Biology, Physics, vol. 36, no. 2, pp. 311–319, 1996. View at Publisher · View at Google Scholar · View at Scopus
  40. A. M. Davis, B. O'Sullivan, R. Turcotte et al., “Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sarcoma,” Radiotherapy and Oncology, vol. 75, no. 1, pp. 48–53, 2005. View at Publisher · View at Google Scholar · View at Scopus
  41. B. O'Sullivan, A. M. Davis, R. Turcotte et al., “Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial,” The Lancet, vol. 359, no. 9325, pp. 2235–2241, 2002. View at Publisher · View at Google Scholar · View at Scopus