Research Article

Prognostic Factors and Treatment Results of High-Grade Osteosarcoma in Norway: A Scope Beyond the “Classical” Patient

Table 1

Characteristics of nonclassical and classical osteosarcoma (OS) patients, 1975–2009.

Nonclassical OS patients (%)Classical OS patients (%) All patientsa (%)

All patients221 (52)203 (48)424 (100)

Gender
 Female108 (49)70 (34)178 (42)
 Male113 (51)133 (66)246 (58)
Axial versus extremity
 Extremity106 (48)203 (100)309 (73)
 Axial115 (52)0115 (27)
Primary metastatic disease
 No134 (61)203 (100)337 (80)
 Yes84 (39)084 (20)
Age
 ≤40 years94 (43)203 (100)297 (70)
 >40 years127 (57)0127 (30)
Tumour size
 ≤10 cm 84 (52)102 (56)186 (54)
 >10 cm78 (48)80 (44)158 (46)
Duration of symptoms
 ≤3 months86 (45)120 (62)206 (53)
 >3 months 107 (55)73 (38)180 (47)
Pathologic fracture
 No187 (85)178 (88)365 (86)
 Yes34 (15)25 (12)59 (14)
ALP
 Normal62 (42)104 (68)166 (55)
 Elevated87 (58)48 (32)135 (45)
LDH
 Normal73 (51)87 (61)160 (56)
 Elevated70 (49)56 (39)126 (44)
Histology
 Osteoblastic97 (44)94 (47)191 (46)
 Chondroblastic30 (14)25 (13)55 (13)
 Fibroblastic20 (9)21 (11)41 (10)
 Other73 (33)59 (30)132 (32)

Missing values equal the difference between the summarized number from each subgroup in the fourth column and the total patients in the study.