A Patient-Derived Xenograft Model of Parameningeal Embryonal Rhabdomyosarcoma for Preclinical Studies

Figure 1

Radiographic imaging and comparative histology of human and PDX tumors: (a) 1 cm × 2 cm enhancing right-sided skull based mass that was invading the hypoglossal nerve canal. (b) H&E slide, 400x of brain biopsy showing sheets of elongated spindled cells with eosinophilic cytoplasm and a myxoid background, consistent with embryonal rhabdomyosarcoma. An H&E slide, 400x from the frontal lobe at autopsy (c), and a section of mouse xenograft, 200x (d), show highly similar morphologic features.

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