Research Article
Age, Tumor Characteristics, and Treatment Regimen as Event Predictors in Ewing: A Children’s Oncology Group Report
Table 1
Characteristics of 1444 patients enrolled in COG studies.
| | Factor | Study | | INT-0091 | INT-0154 (P9354) | AEWS0031 | Total |
| | Number of patients | 398 | 478 | 568 | 1444 | | Median age, years (range) | 12 (0–28) | 12 (0–30) | 12 (0–45) | 12 (0–45) | | 9 years, (%) | 121 (30) | 148 (31) | 162 (28) | 431 (29.9) | | 9–18 years | 227 (57) | 265 (55) | 339 (60) | 831 (57.6) | | 18 years | 50 (13) | 65 (14) | 67 (12) | 182 (12.6) | | Sex, % | | | | | | Men | 57 | 55 | 54 | 55 | | Women | 43 | 45 | 46 | 45 | | Primary sites, (%) | | | | | | Appendicular | 188 (47) | 175 (36) | 195 (34) | 558 (39) | | Thoracic | 69 (17) | 75 (16) | 89 (16) | 233 (16) | | Pelvic | 93 (23) | 70 (15) | 90 (16) | 253 (18) | | Other axial | 48 (12) | 57 (12) | 75 (13) | 180 (12) | | Extraosseous | — | 94 (20) | 119 (21) | 213 (15) | | Missing | 0 (0) | 7 (1.5) | 0 (0) | 7 (0.48) | | Tumor size, (%) | | | | | | 8 cm | 155 (30) | 141 (29.5) | 0 (0) | 296 (10) | | 9–12 cm | 113 (28) | 98 (21) | 0 (0) | 211 (15) | | 13 cm | 64 (16) | 39 (8.2) | 0 (0) | 93 (7) | | Not reported | 66 (17) | 200 (42) | 568 (100) | 834 (57.8) |
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COG = Children’s Oncology Group.
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