Research Article

A Therapeutic Role for Survivin in Mitigating the Harmful Effects of Ionizing Radiation

Figure 2

Mice treated with rAAV-survivin showed fewer signs of damage to the skin and surrounding tissue following 50 Gy of radiation exposure. Mice were monitored daily following the ten-day radiation protocol (a). Both YFP and survivin treated mice initially showed hair loss; however, by five days after the last dosage, there was a significant difference between the two groups in terms of the area of skin ulceration and impaired wound healing (b). Student’s -test was used to compare the groups and demonstrated a significant result. Data are mean ± s.d.; per group. Student’s -test: at five, eight, and ten days after radiation exposure. indicates significance.
(a)
(b)