Cryosurgery as Additional Treatment in Tenosynovial Giant Cell Tumors

Table 2

Indications, treatment details, follow-up, recurrences with their treatments, and complications of patients who received additional cryosurgery.

Location patient ID	Indications for treatment				Follow-up (FU)
	Large expansion	Extra-articular disease	Bone involvement	Cruciate ligaments	Total FU (years)	Recurrence	Time until recurrence (years)	Treatment of recurrence			Complications
								1e	2e	3e
Knee
1	X	X		X	7.1	Yes	1.19	TKA
2	X	X	X	X	9.4	No
3	X			X	5.8	Yes	1.85	SE	Imatinib
4	X	X	X		5.8	No
5	X			X	3.9	Yes	0.73	SE	SE + EBRT	None
6				X	8.3	No
7	X	X	X	X	6.1	Yes	1.47	EBRT	Nilotinib		Infection
8	X		X	X	7.6	No
Hip
9	X	X	X		10.7	Yes	9.03	SE + cryo			Hip dislocation
10	X	X	X		14.9	No
Ankle
11	X	X	X		5.5	No
Elbow
12					7.5	No

Follow-up: from cryosurgery until last patient contact, SE: surgical synovectomy, tSE: two-stage synovectomy (anterior and posterior compartment of the knee in two separate procedures), EBRT: external beam radiation therapy, cryo: cryosurgery, and TKA: total knee arthroplasty.