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Sarcoma
Volume 2016, Article ID 4592768, 7 pages
http://dx.doi.org/10.1155/2016/4592768
Clinical Study

Phase II Trial of Angiotensin-(1-7) for the Treatment of Patients with Metastatic Sarcoma

1Department of Medicine, Section of Hematology and Oncology, Wake Forest School of Medicine, Winston-Salem, NC, USA
2Comprehensive Cancer Center of Wake Forest University, Wake Forest School of Medicine, Winston-Salem, NC, USA
3Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA
4Department of Surgical Sciences, Center for Hypertension and Vascular Research, Wake Forest School of Medicine, Winston-Salem, NC, USA
5Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, USA

Received 25 July 2016; Accepted 20 September 2016

Academic Editor: Shreyaskumar Patel

Copyright © 2016 Paul D. Savage et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • Maria Tamargo, and Juan Tamargo, “Future drug discovery in renin-angiotensin-aldosterone system intervention,” Expert Opinion on Drug Discovery, pp. 1–22, 2017. View at Publisher · View at Google Scholar
  • Yu-Tsai Lin, Hung-Chen Wang, Hui-Ching Chuang, Yi-Chiang Hsu, Ming-Yu Yang, and Chih-Yen Chien, “Pre-treatment with angiotensin-(1–7) inhibits tumor growth via autophagy by downregulating PI3K/Akt/mTOR signaling in human nasopharyngeal carcinoma xenografts,” Journal of Molecular Medicine, 2018. View at Publisher · View at Google Scholar
  • Yingying Mao, Xuejun Wang, Hongwei Li, Renhe Yan, Na Bai, Baihong Chen, Colin Sumners, Shengqi Wang, Huiying Chen, Hongyan Du, Nana Pei, Xinglu Chen, Andrew Li, Jinlong Li, and Yanling Zhang, “Angiotensin 1-7 overexpression mediated by a capsidoptimized AAV8 vector leads to significant growth inhibition of hepatocellular carcinoma in vivo,” International Journal of Biological Sciences, vol. 14, no. 1, pp. 57–68, 2018. View at Publisher · View at Google Scholar