Research Article

Routes to Diagnosis for Suspected Sarcoma: The Impact of Symptoms and Clinical Findings on the Diagnostic Process

Table 5

Median number of days (interquartile intervals) spent in each interval of the diagnostic process from first symptom to decision of diagnosis/treatment.

Patient interval
median (IQI)
Primary care interval
median (IQI)
Local hospital interval
median (IQI)
Sarcoma centre interval
median (IQI)
Diagnostic interval
median (IQI)
Total interval
median (IQI)

All patients54 (12 : 241)8 (1 : 36.5)26.5 (13 : 58)15 (9 : 22)50 (30 : 98)155 (61 : 423)
Gender
Female48.5 (9 : 182)11 (1 : 39.5)23 (13 : 60)16 (11 : 23)52 (31 : 98)144.5 (60 : 341)
Male59 (13 : 319)4 (1 : 35)28 (13 : 54)15 (8 : 22)50 (29 : 99)158 (62 : 507)
Age
<2031 (15 : 84)22 (2 : 73)21 (11 : 58)15 (8 : 20)55 (30 : 139)118 (47 : 259)
20–3976 (21 : 539)12 (1 : 49)36.5 (18.5 : 102)17 (11 : 25)57 (33 : 148)184 (77 : 924)
40–59110 (17 : 349)7.5 (1 : 36)32.5 (16 : 72)15 (8 : 22)62 (31 : 106)225 (78 : 591)
≥6036.5 (4 : 134)3.5 (1 : 33)21 (11 : 43)15 (9 : 23)42.5 (27 : 78)99 (46 : 240)
Pt had or developed lump
No38.5 (1 : 215)22 (4 : 58)24 (9 : 67)19 (11 : 28)57.5 (35 : 116.5)147 (49.5 : 342.5)
Yes59 (17 : 251)3 (1 : 31)28 (15 : 54)15 (9 : 21)49 (28 : 98)156 (63 : 507)
Patient had or developed pain
No33.5 (3 : 236.5)1 (1 : 31)23.5 (12 : 47)15 (9 : 21.5)41 (26 : 84)95 (43.5 : 389.5)
Yes76 (20 : 241)13 (1 : 44)29 (14 : 65.5)16 (9 : 22)58 (34 : 134)182 (77 : 465)
Tumour size
Under 5 cm46 (9 : 200)12 (1 : 40)30 (15 : 62)15 (8 : 22)56 (32 : 106)147 (59 : 383)
Over 5 cm63 (15 : 319)14 (1 : 45)23 (13 : 52)16 (9 : 23)57 (33 : 107)180 (76.5 : 571)
Tumour depth
Subcutaneous86 (15 : 528)1 (1 : 36)28 (15 : 54)13 (8 : 20)42 (28 : 91)181 (60 : 734)
Subfascial58.5 (14 : 234)7 (1 : 29)29 (15 : 56)15 (9 : 21)55 (31.5 : 100.5)147 (65 : 416)
GP suspected malignancy at initial referral
No81 (22 : 319)9 (1 : 45)38 (20 : 78)15 (9 : 22)63 (38 : 139)197 (90 : 690)
Yes45 (11 : 141)4 (1 : 25)18 (9.5 : 28)15 (8 : 21)34 (21 : 58)94 (45 : 215)
Referred from Aarhus local uptake area
No55 (11 : 227)8 (1 : 40)28 (15 : 58)15 (9 : 22)35 (21 : 88)158 (63 : 401)
Yes43 (13 : 323)3 (1 : 28)18 (6 : 47)16 (9 : 25)56 (33 : 106)135 (51 : 469)
Diagnosis
Sarcomas77 (11 : 261)17 (1 : 56)29 (15 : 56)17 (10 : 24)65 (42 : 133)176 (83 : 673)
Other malignancies38 (6 : 97)12.5 (1 : 25)15 (7 : 32)20 (14 : 26)44 (27.5 : 68)103 (49.5 : 202.5)
Benign54 (13 : 296)4 (1 : 35)28 (16 : 62)15 (8 : 21)48 (29 : 91)158 (59 : 507)
Malignancy grade
Low-grade213 (26 : 963)21.5 (1 : 50)29 (19 : 47)17 (8 : 23)60 (43 : 103)250 (108 : 1665)
High-grade41 (8 : 154)17 (1 : 57)29 (13 : 58)17 (13 : 25)71 (42 : 140)164 (69 : 376)

= total number of patients with available dates for calculation of this interval.
Analysis included only patients with data for tumor size measured on MRI/CT or histology.
Analysis included only patients with soft tissue tumors.
Analysis included only patients with data available for this variable. Patients who were not seen by the GP and patients where the GP had not answered the question were excluded from the analysis.
Analysis included only sarcoma patients.