Clinical Study
Neoadjuvant Ifosfamide and Epirubicin in the Treatment of Malignant Peripheral Nerve Sheath Tumors
Table 1
Clinical features of patients.
| Patient | Gender | Age at diagnosis | Tumor site | NF status | Initial path | Grade | Cycles of chemo | Decrease in tumor (%) | Final path | Clinical status | Overall survival (months) |
| Patient 1 | M | 59 | Axilla | Yes | Neuroepithelial differentiation of MPNST | Unable to review | 5 | 47 | Residual fibroadipose tissue and metastatic sarcoma in 3/12 lymph nodes | NED | 36 |
| Patient 2 | M | 27 | Mediastinum | Yes | MPNST | FNCLCC Grade 2 | 11 | 39 | MPNST and areas of lung with pneumocyte hyperplasia | Deceased | 14 |
| Patient 3 | M | 29 | RP | No | MPNST | FNCLCC Grade 3 | 6 | 15 | MPNST with 80% treatment effect | NED | 42 |
| Patient 4 | F | 54 | Brachial plexus | No | MPNST | FNCLCC Grade 2 | 5 | 33 | CR without surgery | NED | 43 |
| Patient 5 | M | 35 | Neck | Yes | MPNST | FNCLCC Grade 3 | 5 | 0 | MPNST with 20% treatment effect | NED | 9 |
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RP = retroperitoneum.
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