Clinical Study

Neoadjuvant Ifosfamide and Epirubicin in the Treatment of Malignant Peripheral Nerve Sheath Tumors

Table 1

Clinical features of patients.

Patient GenderAge at diagnosisTumor siteNF statusInitial pathGradeCycles of
chemo
Decrease in tumor (%)Final pathClinical statusOverall
survival
(months)

Patient 1M59AxillaYesNeuroepithelial differentiation of MPNSTUnable to review547Residual fibroadipose tissue and metastatic sarcoma in 3/12 lymph nodesNED36

Patient 2M27MediastinumYesMPNSTFNCLCC Grade 21139MPNST and areas of lung with pneumocyte hyperplasiaDeceased14

Patient 3M29RPNoMPNSTFNCLCC Grade 3615MPNST with 80% treatment effectNED42

Patient 4F54Brachial plexusNoMPNSTFNCLCC Grade 2533CR without surgeryNED43

Patient 5M35NeckYesMPNSTFNCLCC
Grade 3
50MPNST with 20% treatment effectNED9

RP = retroperitoneum.