Pasteurized Autograft-Prosthesis Composite Reconstruction May Not Be a Viable Primary Procedure for Large Skeletal Defects after Resection of Sarcoma

Table 2

Causes of 52 pasteurized bone-prosthesis composite failure and final status by location.

Tumor location; (number of cases, percent)	Infection; (percent)	LR	Fracture of pasteurized bone	Loosening + nonunion or resorption	Metal failure + nonunion	Final limb status
						TP	Arthrodesis	Amputation	APC	Pseudo-; arthrosis
Femur	6/18	0	3/18	5/18	4/18	8	3	6	1	0
(18/76, 24%)	(33%)	(0%)	(17%)	(28%)	(22%)
Humerus	0	0	2/5	2/5	1/5	4	0	0	1	0
(5/12, 42%)	(0%)	(0%)	(40%)	(40%)	(20%)
Pelvis	3/10	1/10	6/10	0	0		0	0		7
(10/15, 67%)	(30%)	(10%)	(60%)	(0%)	(0%)
Tibia	9/19	1/19	0	5/19	4/19	8	8	1	2	0
(19/39, 49%)	(47%)	(5%)	(0%)	(26%)	(21%)
Total	18/52	2/52	11/52	12/52	9/52	23	11	7	4	7
(52/142, 36.6%)	(35%)	(4%)	(21%)	(23%)	(17%)
Average duration	16.8	47.7	87.7	68.1	60.4	56.4	36.8	24.0	94.9	53.8
(range)	(1.1–120.3)	(32.0–63.4)	(3.7–200.6)	(16.2–168.5)	(14.7–162.9)	(6.7–125.8)	(2.8–142.8)	(2.8–116.2)	(16.2–162.9)	(1.1–200.6)

LR: local recurrence, TP: tumor prosthesis, and APC: allograft prosthesis composite. Saddle prosthesis.