Table 6: Univariate analysis of overall and event-free survival.

SurvivalNumber of patientsPercentEvent-free survivalOverall survival
Variable5 year (%)SE (%) (log-rank)5 year (%)SE (%) (log-rank)

Total23
Age
 <32 years (median)125264150.43861150.828
 >32 years114839216720
Sex
 Male135744180.7913917.50.235
 Female104363188910.5
Tumor site
 Tarsus167049160.90357150.503
 Other73071178018
Tumor size
 <31.5 cm3 (median)55080180.78680180.366
 >31.5 cm355067276727
Primary metastases
 No208766130.00578110.008
 Yes3130000
AP
 Normal157560160.21657160.568
 Elevated52530245325
LDH
 Normal168468140.07662150.291
 Elevated316003327
Duration of symptoms
 <154 days (median)115576160.18876160.463
 >154 days94529225120
Delay of chemotherapy
 <21 days83558190.53273170.441
 >21 days156552175717
Timing of operation
 After preoperative chemotherapy187852140.92964130.587
 Primary surgery52267276727
Type of surgery
 Resection41775220.66075220.347
 Amputation198345156014
Surgical remission
 Complete remission219560130.00072120.000
 Macroscopic residual290000
Tumor response
 Good42438290.98067270.435
 Poor137664155916

5-year event-free and overall survival and values in the log-rank test for all variables (see Data collection and Definition of Variables). SE = standard error;  = two-sided values.