Research Article

Treatment Patterns and Survival among Adult Patients with Advanced Soft Tissue Sarcoma: A Retrospective Medical Record Review in the United Kingdom, Spain, Germany, and France

Table 6

Treatment sequencing: most common first- and second-line treatment regimens.

First lineN (%)Second lineN (%)

Doxorubicin330 (40.9)Ifosfamidea63 (19.1)
Pazopanib24 (7.3)
Trabectedin19 (5.8)
Docetaxel + gemcitabine15 (4.5)
Paclitaxel5 (1.5)
Others16 (4.8)
No treatment188 (57)

Doxorubicin + ifosfamidea153 (19.0)Docetaxel + gemcitabine38 (24.8)
Pazopanib21 (13.7)
Trabectedin17 (11.1)
Others23 (15.0)
No treatment54 (35.3)

Docetaxel + gemcitabine70 (8.7)Doxorubicin13 (18.6)
Pazopanib7 (10)
Doxorubicin + ifosfamidea4 (5.7)
Ifosfamidea3 (4.3)
Others9 (12.9)
No treatment34 (48.6)

Paclitaxel34 (4.2)Doxorubicin3 (8.8)
Ifosfamidea1 (2.9)
No treatment30 (88.2)

Ifosfamide-mesna33 (4.1)Doxorubicin3 (9.1)
Others3 (9.1)
No treatment27 (81.8)

aMesna was always coadministered with ifosfamide.