Myxoid Liposarcoma: Treatment Outcomes from Chemotherapy and Radiation Therapy

Table 1

Demographic information.

Total number of patients	85
Male	48
Female	37
Median age (years)	42 (range, 18–88 years)
Patients treated with preoperative radiation therapy	67 (78.8%)
Patients treated with postoperative radiation therapy	15 (17.6%)
Patients treated with pre- and postoperative radiation therapy	7 (8.2%)
Patients treated with postoperative radiation therapy only	8 (9.4%)
Patients not treated with radiation therapy	10 (11.8%)
Number of patients treated with chemotherapy	39
Location of tumor
Right thigh	30 (35.3%)
Left thigh	28 (32.9%)
Right lower leg	6 (7.1%)
Left lower leg	4 (4.7%)
Right knee	3 (3.5%)
Buttock	3 (3.5%)
Left knee	2 (2.4%)
Abdomen	2 (2.4%)
Paraspinal	1 (1.2%)
Chest wall	1 (1.2%)
Left shoulder	1 (1.2%)
Back	1 (1.2%)
Vulva	1 (1.2%)
Head and neck	1 (1.2%)
Tumor size
Mean (cm)	12.0
Median (cm)	10.0
Range (cm)	1.3–35
Median preoperative radiation dose (cGy)	5000 (range, 2000–7100)
Median postoperative radiation dose (cGy)	1600 (range, 1000–7020)
Median postoperative dose in patients receiving preoperative radiation therapy (cGy)	1600 (range, 1000–2200)
Median postoperative dose in patients not receiving preoperative radiation therapy (cGy)	6150 (range, 5940–7020)
Margin status (number of patients)
Gross positive	2 (2.4%)
Microscopically positive	12 (14.1%)
Close (<1 mm)	50 (58.8%)
Negative	19 (22.3%)
Margin status not reported	2 (2.4%)
Local failures	4/85 (4.7%)
Local failures (patients treated with preoperative radiation therapy)	2/67 (3.0%)
Local failures (patients not treated with preoperative therapy)	2/18 (11%)