Improving Long-Term Outcomes for Patients with Extra-Abdominal Soft Tissue Sarcoma Regionalization to High-Volume Centers, Improved Compliance with Guidelines or Both?
Table 3
Multivariable analysis for overall mortality.
Variable
Comparison
Adjusted HR
95% CI
value
Volume
2nd versus 1st tercile
0.94
0.85
1.04
0.24
3rd versus 1st tercile
0.92
0.82
1.02
0.12
Age
Per 1-year older
1.03
1.03
1.04
<0.001
Sex
Male versus female
1.20
1.10
1.31
<0.001
Race
White versus black/others
0.92
0.81
1.04
0.18
Insurance
Yes versus no
0.81
0.66
1.01
0.06
Income
$30,000–$34,999 versus < $30,000
0.93
0.79
1.09
0.37
$35,000–$45,999 versus < $30,000
1.01
0.86
1.19
0.88
$46,000+ versus < $30,000
0.88
0.74
1.05
0.16
Education
20%–28.9% versus 29%+
0.94
0.81
1.08
0.36
14%–19.9% versus 29%+
0.89
0.76
1.04
0.13
<14% versus 29%+
0.88
0.75
1.03
0.11
Comorbidity
1 versus 0
1.14
1.02
1.28
0.02
2+ versus 0
1.81
1.50
2.18
<0.001
Site
Head/neck versus extremity
1.65
1.38
1.97
<0.001
Overlapping versus extremity
1.45
1.15
1.83
0.002
Trunk versus extremity
1.19
1.09
1.31
<0.001
Tumor size
5–10 cm versus < 5 cm
1.51
1.35
1.69
<0.001
>10 cm versus < 5 cm
2.43
2.16
2.74
<0.001
Grade
Moderately differentiated versus well differentiated
1.70
1.40
2.07
<0.001
Poorly differentiated versus well differentiated
3.34
2.84
3.94
<0.001
Undifferentiated versus well differentiated
3.16
2.66
3.76
<0.001
Cell type not determined versus well differentiated
