Research Article

Primary Cardiac Sarcoma: A Rare, Aggressive Malignancy with a High Propensity for Brain Metastases

Table 1

Patient demographics and disease characteristics.

No. of patients (%)

Male13 (33)
Female26 (67)
Median tumor size in cm (range)6.5 (1.7–16)
Median no. of total chemotherapy regimens2 (range 1–6)
Primary tumor location
 Right heart16 (41)
 Left heart18 (46)
 Pericardium5 (13)
Histology
 Angiosarcoma14 (36)
 High-grade undifferentiated pleomorphic sarcoma10 (26)
 Leiomyosarcoma5 (13)
 Intimal sarcoma3 (8)
 Fibrosarcoma2 (4)
 Other5 (13)
Metastatic disease present at diagnosis18 (46)
Sites of metastases
 Lung10 (55)
 Bone7 (39)
 Liver5 (28)
 Brain4 (22)
 Pancreas1 (5)
 Adrenal1 (5)
Treatment
 Surgery25 (58)
  R03 (12)
  R19 (36)
  R211 (44)
  Unknown2 (8)
 Chemotherapy28 (72)
 Radiation to cardiac tumor3 (8)
Median age in years (range)41 (2–77)