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Sarcoma
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2019
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Article
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Tab 1
Research Article
Adjuvant Chemotherapy in Uterine Leiomyosarcoma: Trends and Factors Impacting Usage
Table 1
Demographic and clinical characteristics of uterine LMS patients stratified by receipt of chemotherapy.
Characteristics
Chemotherapy
No chemotherapy
Number
%
Number
%
Age at diagnosis,
y
<0.0001
18–39
66
7.1
107
6.0
40–49
270
28.8
467
26.0
50–64
475
50.7
794
44.2
65+
125
13.4
428
23.8
Race (missing from analysis:
)
0.7531
White
701
79.7
1327
78.4
African American
179
20.3
365
21.6
Hispanic (missing from analysis:
)
0.0292
Yes
79
8.8
111
6.5
No
814
91.2
1596
93.5
Comorbidities (Charlson/Deyo score)
0.1509
0
787
84.1
1460
81.3
1
126
13.5
275
15.3
2
23
2.5
61
3.4
Insurance status (missing from analysis:
)
<0.0001
Medicare
122
13.2
442
24.9
Private
657
71.0
1112
62.8
Medicaid/Other government
89
9.6
120
6.8
None
57
6.2
98
5.5
Median household income ($) (missing from analysis:
)
0.4726
<38,000
164
17.7
329
18.6
38,000–47,999
198
21.4
366
20.7
48,000–62,999
252
27.2
441
24.9
>63,000
311
33.6
634
35.8
Education (% no high school diploma) (missing from analysis:
)
0.0355
≥21
166
17.9
321
18.1
13–20.9
185
20.0
437
24.7
7–12.9
335
36.2
576
32.5
<7
239
25.8
436
24.6
Location of patient (missing from analysis:
)
0.0902
Large metropolitan
574
62.7
1013
58.7
Small metropolitan
236
25.8
484
28.0
Suburban
75
8.2
145
8.4
Rural
30
3.3
85
4.9
Hospital volume (cases per year)
0.0181
0.09
38
4.1
99
5.5
0.18–0.27
103
11.0
256
14.3
0.36–0.55
181
19.3
353
19.7
0.64–7.27
614
65.6
1088
60.6
Regional lymph nodes positive (missing from analysis:
)
<0.0001
Yes
30
8.0
13
2.0
No
347
92.0
642
98.0
Stage
<0.0001
1
676
72.2
1541
85.8
2
64
6.8
116
6.5
3
196
20.9
139
7.7
Year of diagnosis
<0.0001
2004–2009
345
36.9
1005
56.0
2010–2014
591
63.1
791
44.0
Radiation (missing from analysis:
)
0.0406
Yes
225
24.3
373
20.9
No
700
75.7
1413
79.1
Oophorectomy (missing from analysis:
)
0.6492
Yes
716
84.0
1437
84.7
No
136
16.0
259
15.3