Sarcoma / 2019 / Article / Tab 1

Research Article

How Effective Are Noninvasive Tests for Diagnosing Malignant Peripheral Nerve Sheath Tumors in Patients with Neurofibromatosis Type 1? Diagnosing MPNST in NF1 Patients

Table 1

Descriptive statistics and potential predictors of malignancy for the 70 peripheral nerve sheath tumors in our study population of 41 NF1 patients. These included patient characteristics (age and gender), PET findings (SUVmax, SUVpeak, and TLR), MRI findings (size, depth relative to the fascia, and necrosis) and clinical findings (pain, tumor enlargement, and nerve symptoms), and histologic diagnosis.

Patient characteristicsAge (years)Mean30
Median28
Range9–62
Gender (# of tumors each)Female41
Male29

Clinical findingsPainYes46
No14
EnlargementYes46
No14
Nerve symptomsYes23
No37

MRI findingsSize (cm)Mean6.5
Median5.4
Range1.5–20.0
Depth (relative to fascia)Superficial7
Deep63
NecrosisYes19
No18

PET findingsSUVmaxMean7.9
Median7.4
Range0.7–22.6
SUVpeakMean6.4
Median5.0
Range0.5–18.7
TLRMean4.0
Median3.7
Range0.4–11.9

HistologyMalignantYes36
No34

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