Revisiting the Role of Radiation Therapy in Chondrosarcoma: A National Cancer Database Study
Table 2
Tumor and treatment characteristics.
N (%)
No radiation (n = 4742)
Radiation (n = 680)
High dose >60 Gy (n = 228)
Low dose 40–60 Gy (n = 204)
Palliative <40 Gy (n = 107)
Conventional (n = 294)
Advanced (n = 245)
Tumor size ≥ 5 cm
2628 (66)
325 (61)
100 (53)
122 (75)
59 (76)
168 (71)
86 (45)
Tumor site
Axial
2012 (44)
507 (78)
180 (83)
141 (73)
63 (64)
190 (69)
221 (92)
Appendicular
2600 (56)
140 (22)
37 (17)
53 (27)
36 (36)
84 (31)
20 (8)
Grade
Low
1868 (45)
144 (27)
57 (30)
36 (24)
11 (13)
48 (21)
69 (35)
Intermediate
1541 (37)
235 (45)
90 (47)
68 (46)
36 (44)
102 (45)
94 (48)
High
773 (18)
146 (28)
43 (23)
44 (30)
35 (43)
79 (35)
34 (17)
Metastases at diagnosis
191 (4)
73 (11)
7 (3)
18 (9)
43 (42)
48 (17)
9 (4)
Surgery
4328 (91)
513 (75)
190 (83)
152 (75)
56 (52)
201 (68)
199 (81)
Margin
Positive
415 (12)
168 (44)
68 (49)
42 (34)
15 (38)
60 (38)
80 (60)
Chemotherapy
249 (5)
91 (14)
19 (9)
27 (14)
28 (26)
48 (17)
18 (8)
For each value, the (%) reflects only the proportion of patients with known values for each variable (unknown values not included in %). Statistical comparisons included RT vs. none, palliative vs. low vs. high doses (non-SRS modalities), and conventional vs. advanced modalities. Fisher’s exact or Pearson chi-square tests were performed for categorical variables. Two-tailed t-test or ANOVA was performed for numerical variables (age). Statistical significance indicated by for , for , and for .
