|
| Original diagnosis | Second-opinion diagnosis | Comments |
|
| Malignant to malignant, 12 cases | | |
| Malignant peripheral nerve sheath tumor | Dedifferentiated liposarcoma | MDM2 amplified |
| Atypical neoplasm | Well-differentiated liposarcoma | MDM2 amplified |
| Myxoid sarcoma | Dedifferentiated liposarcoma | MDM2 failed |
| Pleomorphic leiomyosarcoma | Dedifferentiated liposarcoma | MDM2 amplified |
| Leiomyosarcoma | Dedifferentiated liposarcoma | MDM2 amplified |
| Sarcomatoid renal cell carcinoma | Dedifferentiated liposarcoma | |
| Pleomorphic sarcoma | Dedifferentiated liposarcoma | |
| Sarcoma | Dedifferentiated liposarcoma with rhabdomyosarcomatous areas | MDM2 amplified |
| Leiomyosarcoma | Dedifferentiated liposarcoma | MDM2 amplified |
| Undifferentiated sarcoma | Dedifferentiated liposarcoma | MDM2 amplified, ALK negative, CDK4 focal, INI1 + |
|
| Low-grade sarcoma | Dedifferentiated liposarcoma | |
| Undifferentiated sarcoma | Well-differentiated liposarcoma | MDM2 amplified |
|
| Malignant to benign, 7 cases | | |
| 7 cases of liposarcoma | Lipoma with or without fat necrosis | MDM2 not amplified in all cases, but CDK4 positive in 1 case |
|
| Benign to benign, 5 cases | | |
| Spindle cell lipoma | Fibrolipoma | MDM2 not amplified |
| Hamartoma | Fibrolipoma | |
| Spindle cell lipoma | Lipoblastoma | |
| Fibrous hamartoma of infancy | Lipoblastomatosis | |
| Myxoma | Spindle cell lipoma | |
|
| Benign to malignant, 5 cases | | |
| 4 lipomas, 1 stromal lesion | Well-differentiated liposarcoma | MDM2 amplified in all cases |
|
| Intermediate to malignant, 2 cases | | |
| Inflammatory myofibroblastic tumor | Dedifferentiated liposarcoma | MDM2 amplified |
| Solitary fibrous tumor | Dedifferentiated liposarcoma | MDM2 amplified, CDK4 positive, MUC4, DOG1, ALK negative |
| Nondiagnostic material, 1 case | Dedifferentiated liposarcoma | MDM2 amplified |
|
