Diagnostic Differences in Expert Second-Opinion Consultation Cases at a Tertiary Sarcoma Center

Table 6

Nerve sheath tumors with discrepancy in opinion.

Original diagnosis	Second-opinion diagnosis
Malignant to malignant, 1 case
Melanoma or less likely cellular schwannoma	Malignant peripheral nerve sheath tumor
Malignant to benign, 3 cases
Low-grade sarcoma	Schwannoma
Low-grade spindle cell neoplasm	Schwannoma/neurofibroma
Spindle cell liposarcoma	Neurofibroma
Benign to benign, 1 case
Neural tumor	Plexiform cellular schwannoma
Benign to intermediate, 2 cases
Spindle cell lesion	Myxoid atypical neurofibroma
Granular cell tumor	Atypical granular cell tumor
Benign to malignant, 3 cases
Schwannoma	Malignant schwannoma
Benign neural tumor	Low-grade MPNST
Granular cell tumor	Malignant granular cell tumor
Intermediate to malignant, 1 case
Fibromatosis	Low-grade MPNST

MPNST: malignant peripheral nerve sheath tumor.