Research Article

A Quantitative Structure-Activity Relationship and Molecular Modeling Study on a Series of Biaryl Imidazole Derivatives Acting as H+/K+-ATPase Inhibitors

Table 4

Data related to Lipinski rules. The last four compounds are licensed compounds given for comparision.

Predicted Compound in Table 2Lipinski Parameters
MWHAHDlog P

1324.377522.51
2413.467850.84
3411.494750.49
4407.555750.07
5439.504850.24
6437.534850.03
7437.538950.16
8409.527850.41
9411.497850.63
10409.525750.28
Omeprazole383.370812.18
Lansoprazole369.361713.03
Rabeprazole339.388512.56
Pantoprazole345.416512.43