Research Article

Ultrastructural Alterations of Myelinated Fibers and Oligodendrocytes in the Prefrontal Cortex in Schizophrenia: A Postmortem Morphometric Study

Figure 5

Electron micrographs of white matter from control brain (a) and from the brains of subjects with schizophrenia (b–d). Both thinly myelinated (b, c) and axons with focal lysis of myelin sheath (d) as well as some axons with abnormally thick myelin sheaths (Figure 1(b)) were observed in schizophrenia in contrast to controls. Ap: astrocytic process, Mg: microglial cell. Ol: oligodendrocyte. Scale bars = 2 μm.
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