Twenty Years of Schizophrenia Research in the Northern Finland Birth Cohort 1966: A Systematic Review

Table 3

Factors associated with the use of antipsychotic medication in the Northern Finland Birth Cohort 1966.

Factors	Effect of higher use of antipsychotic medication
Sex	Females used more often medication [36]
Age at onset of psychosis	No association [36]
Psychiatric hospital treatment	Increased need of hospital treatment [36]
Clinical measures (PANSS, CGI, SOFAS, and remission)	Poorer clinical and social outcome [36]
Occupational functioning	Higher rate of disability pensions and lower rate of employment [36]
Brain volume loss	Increased brain loss [37]
Change of cognition	Decline of verbal learning and memory [38]
Suicidal ideation	No association when symptoms of depression and anxiety were controlled for [39]
Hyperlipidemia	Increased risk of hyperlipidemia [40]

PANSS = Positive and Negative Syndrome Scale, CGI = Clinical Global Impression, and SOFAS = Social and Occupational Functioning Assessment Scale.