Attitude towards Antipsychotic Medications in Patients Diagnosed with Schizophrenia: A Cross-Sectional Study at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia

Table 4

Factors associated with attitude towards antipsychotic medications during multiple linear regression analysis (n=393).

Variables	Crude unstandardized β coefficient (95% CI)	Adjusted unstandardized β coefficient (95% CI)
Residence
Rural	0	0
Urban	-0.59 (-1.06, -0.12)	-0.10 (-0.29, 0.11)
Age of onset of illness	0.03 (0.002, 0.060)	0.02 (-0.20, 0.24)
duration of illness
>10 years	0	0
5-10 years	0.36 (-0.10, 0.82)	-0.08 (-0.31, 0.15)
≤5 years	-2.49 (-2.92, -2.05)	-0.39 (-0.63, -0.15)
PANSS positive score	-0.2 (-0.209, -0.181)	-0.07 (-0.09, -0.05)
PANSS negative score	-0.19 (-0.21, -0.17)	-0.04 (-0.06, -.02)
PANSS general psychopathology score	-0.09 (-0.10, -0.08)	-0.004 (-0.01, 0.004)
BIS total score	0.49 (0.46, 0.52)	0.24 (0.20, 0 .27 )
Class of drugs
SGAs	0	0
FGAs+ SGAs	-0.58 (-1.19, 0.03)	-0.17 (-0.47, 0.13)
FGAs	-1.89 (-2.30, -1.48)	-0.35 (-0.55, -0.14)
No of Antipsychotics
Single	0	0
≥2	-1.64 (-2.16, -1.11)	-0.15 (-0.42, 0.12)
Route of use
Oral	0	0
Parenteral	-1.36 (-1.83, -0.89)	0.02 (-0.21, 0.25)
Sedation side effects
No	0	0
Yes	-2.59 (-2.99, -2.20)	-0.28 (-0.52,-0.02)
EPS symptoms
No	0	0
Yes	-2.59 (-2.96, -2.23)	-0.34 (-0.59, -0.01)
Sexual dysfunction
No	0	0
Yes	-0.75 (-1.19, -0.31)	0.01 (-0.19, 0.20)
Current substance use
No	0	0
Yes	-1.54 (-2.00, -1.08)	0.02 (-0.20, 0.24)

Note; p<0.05, p< 0.01, p< 0.001
Adjusted R²= 79.9%, F-test p-value<0.001.