Polygenic Risk Scores for Subtyping of Schizophrenia
Table 4
Changes of laboratory tests between baseline and end of Phase I trial.
Mean Diff
-value
df
95% CI
value
HDL
All subjects
−0.07
−0.15
419
−0.99–0.85
0.8833
Class I
−2.25
−3.04
168
−3.70–−0.79
0.0027
Class II
−0.68
−0.61
78
−2.90–1.53
0.5406
Class III
2.94
1.98
49
−0.05–5.93
0.0537
Class IV
1.93
1.55
43
−0.57–4.44
0.1274
Class V
2.22
2.30
77
0.30–4.13
0.0239
Calcium
All subjects
0.08
3.61
419
0.04–0.12
0.0003
Class I
0.05
1.28
168
−0.02–0.13
0.2041
Class II
0.08
1.80
77
−0.01–0.18
0.0763
Class III
0.07
1.10
50
−0.06–0.21
0.2757
Class IV
0.12
1.79
43
−0.02–0.26
0.0806
Class V
0.14
2.71
77
0.04–0.24
0.0084
Phosphorus
All subjects
0.10
2.99
419
0.04–0.17
0.0029
Class I
0.02
0.41
168
−0.09–0.14
0.6858
Class II
0.12
1.49
77
−0.04–0.28
0.1409
Class III
0.19
2.26
50
0.02–0.37
0.0282
Class IV
0.16
1.54
43
−0.05–0.38
0.1318
Class V
0.17
2.25
77
0.02–0.32
0.0276
Lymphocytes
All subjects
0.23
0.55
416
−0.58–1.04
0.5806
Class I
0.67
1.06
164
−0.58–1.90
0.2915
Class II
0.68
0.68
78
−1.11–2.47
0.4531
Class III
−0.14
−0.12
52
−2.53–2.25
0.9084
Class IV
−3.12
−2.86
43
−5.32–−0.92
0.0065
Class V
1.00
0.90
75
−1.21–3.21
0.3684
Neutrophils
All subjects
−0.48
−1.02
416
−1.40–0.44
0.3092
Class I
−0.96
−1.42
164
−2.30–0.38
0.1588
Class II
−0.98
−0.91
78
−3.12–1.16
0.3660
Class III
0.34
0.23
52
−2.58–3.26
0.8161
Class IV
3.04
2.39
43
0.47–5.61
0.0214
Class V
−1.51
−1.22
75
−3.97–0.96
0.2265
Mean Diff: mean difference between the baseline and Phase I; 95% CI: 95% confidence interval; -value: test value; df: degree of freedom; values ≤0.05 were highlighted by bold; HDL: high-density lipoproteins.
