Schizophrenia Research and Treatment

Oligodendrocytes in Schizophrenia

Publishing date
15 Jul 2011
Submission deadline
15 Jan 2011

Lead Editor

1Department of Anatomy, Southern Illinois University Carbondale, Carbondale, IL 62901, USA

2Department of Psychiatry, Mount Sinai School of Medicine, NY 10128, USA

3Department of Psychiatry and Biobehavioral Sciences, The David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 6968, USA

4Department of Psychiatry, Harvard Medical School, Boston, MA 02215, USA

Oligodendrocytes in Schizophrenia


Schizophrenia is a heterogeneous brain disease with disturbances in a range of human characteristics including thought, perception, emotion, drive, and behavior. Although the etiology and pathophysiology of this disease remain largely unknown, significant advances in schizophrenia research have been achieved in recent years through the use of neuroimaging, genetic, and molecular methods. There is increasing evidence from human postmortem and imaging studies showing abnormalities in the white matter of brains of patients with schizophrenia. This advance has led researchers to investigate possible roles of the myelin sheath forming cells–oligodendrocytes in the pathophysiology and treatment of schizophrenia.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to explore roles of oligodendrocytes in the pathophysiology and treatment of schizophrenia. Potential topics include, but are not limited to:

  • White Matter changes in schizophrenia
  • Oligodendrocyte abnormalities in schizophrenia
  • Animal models of schizophrenia with white matter changes or experimentally induced oligodendrogliapathy
  • Effects of antipsychotics on white matter
  • Effects of antipsychotics on oligodendrocytes
  • Central nervous system mechanisms of myelination, demyelination and remyelination
  • Strategies and approaches to the treatment of white matter and oligodendroglial abnormalities in schizophrenia

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2011
  • - Article ID 249768
  • - Editorial

Oligodendrocytes in Schizophrenia

Haiyun Xu | Vahram Haroutunian | ... | Martha E. Shenton
  • Special Issue
  • - Volume 2011
  • - Article ID 826976
  • - Review Article

White Matter Abnormalities and Animal Models Examining a Putative Role of Altered White Matter in Schizophrenia

Haiyun Xu | Xin-Min Li
  • Special Issue
  • - Volume 2011
  • - Article ID 709523
  • - Research Article

Diffusion Tensor Imaging, Structural Connectivity, and Schizophrenia

Thomas J. Whitford | Marek Kubicki | Martha E. Shenton
  • Special Issue
  • - Volume 2011
  • - Article ID 542896
  • - Research Article

Abnormal Behaviors and Microstructural Changes in White Matter of Juvenile Mice Repeatedly Exposed to Amphetamine

Hong-Ju Yang | Lijun Wang | ... | Haiyun Xu
  • Special Issue
  • - Volume 2011
  • - Article ID 325789
  • - Research Article

Ultrastructural Alterations of Myelinated Fibers and Oligodendrocytes in the Prefrontal Cortex in Schizophrenia: A Postmortem Morphometric Study

Natalya A. Uranova | Olga V. Vikhreva | ... | Diana D. Orlovskaya
  • Special Issue
  • - Volume 2011
  • - Article ID 174689
  • - Research Article

Age-Related Increase in the Number of Oligodendrocytes Is Dysregulated in Schizophrenia and Mood Disorders

Victor Vostrikov | Natalya Uranova
Schizophrenia Research and Treatment
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