Research Article

PKG and PKC Are Down-Regulated during Cardiomyocyte Differentiation from Embryonic Stem Cells: Manipulation of These Pathways Enhances Cardiomyocyte Production

Table 1

Significance comparing treated groups to controls (for data points in Figure 3(a)) % of EBs beating.

DT-3 compared to controls

Day 12: P<.02Day 13: P<.002Day 14: P<.008Day 15: P<.005Day 16: P<.002Day 17: P<.002

DT-3 + PKCζ inhibitor compared to controls

Day 12: P<.04Day 13: P<.0005Day 14: P<.001Day 15: P<.0001Day 16: P<.001Day 17: P<.05

DT-3 + PKCβ inhibitor compared to controls

Day 12: P<.001Day 13: P<.003Day 14: P<.0008Day 15: P<.001Day 16: P<.001Day 17: P<.003