Effect of Bone Marrow-Derived Mesenchymal Stem Cells on Endotoxin-Induced Oxidation of Plasma Cysteine and Glutathione in Mice
Effect of BMDMSC infusion on endotoxin-induced inflammatory response. C57BL/6J mice were treated with 1 mg/kg i.p LPS followed by i.v infusion of either 500,000 BMDMSC (LPS/BMDMSC), or 0.1 mL Saline (LPS/Saline) alone. At 2 hours, 6 hours, and 24 hours mice were sacrificed and plasma was collected for analysis of TNF- (a), IFN-γ (b), and IL-1 (c). Data are expressed as means + SEM. aValues in LPS/BMDMSC group significantly different from time-matched LPS/Saline group.