Efficient Non-Viral Integration and Stable Gene Expression in Multipotent Adult Progenitor Cells
Table 2
C31 and SB chromosome junction sequences recovered from rat MAPC. Around 10 each of drug-resistant clones obtained with PhiC31 integrase and SB transposase were chosen at random to determine the site of genomic integration. Most clones showed more than one integration event, consistent with southern blot results. Exact genomic locations were determined by comparison of the chromosomal junction sequence with that of the rat genome.